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Psychiatry Investig > Volume 15(2); 2018 > Article
Psychiatry Investigation 2018;15(2):226-229.
DOI:    Published online December 14, 2017.
A Neuroleptic Malignant Syndrome Without Rigidity
İlker Özdemir1, Erkan Kuru2, Yasir Safak3, Rıza Gökçer Tulacı4
1Doç. Dr. Mustafa Kalemli Tavşanlı State Hospital, Psychiatry Clinic, Kütahya, Turkey
2Boylam Private Psychiatric Hospital, Ankara, Turkey
3Dışkapı Yıldırım Beyazıt Teaching and Research Hospital, Psychiatry Clinic, Ankara, Turkey
4Uşak State Hospital, Psychiatry Clinic, Uşak, Turkey
Correspondence  İlker Özdemir ,Tel: +905055873405, Fax: +902746151426, Email:
Received: January 3, 2017   Revised: May 28, 2017   Accepted: June 5, 2017   Published online: December 14, 2017
Neuroleptic malignant syndrome (NMS) is an uncommon but potentially lethal idiosyncratic reaction which may emerge in the aftermath of the treatments with neuroleptics demonstrating itself with the symptoms of altered consciousness, high fever, impaired autonomic functions, and muscle rigidity. Although various risk factors have been identified for NMS, its etiology is not completely known. The mortality and morbidity related with NMS could be reduced by early diagnosis, interruption of the neuroleptics used within a short period and aggressive treatment. Our case is different from general NMS cases due to lack of rigidity. A NMS case which developed within a short time in the aftermath of multiple antipsychotic use and wherein no rigidity was observed shall be discussed in this case report.
Keywords: Neuroleptic malignant syndrome, Muscular rigidity, Antipsychotic agents.


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