Psychiatry Investigation

Review Article

February 28, 2023

Reflections on the Lack of Consideration of Ethnic Ancestry to Stratify Clozapine Dosing

Jose de Leon

Psychiatry Investig. 2023;20(3):183-195.

This review article argues against trusting standard clozapine references, including the US package insert, because they do not include advances in the sciences of pharmacokinetics and pharmacovigilance and ignore the...

Original Article

March 22, 2023

Breviscapine Ameliorates Fear Extinction and Anxiety in BALB/cJ Mice

Wei Liang, Jing Huang, Shuya Yang, Peng Huang, Jun Chen, Chen Chen, Qun Yang, Fengzhan Li

Psychiatry Investig. 2023;20(3):205-211.

Objective In this research, the influence of breviscapine on anxiety, fear elimination, and aggression and the potential mechanism was investigated. Methods Anxiety and locomotion were analyzed by elevated plus maze and...

Original Article

March 22, 2023

Atomoxetine and Fluoxetine Activate AMPK-ACC-CPT1 Pathway in Human SH-SY5Y and U-87 MG Cells

Songhee Jeon, Jeong-Eun Park, Young Ho Do, Renata Santos, Seong Mi Lee, Byung-Nyun Kim, Jae Hoon Cheong, Yeni Kim

Psychiatry Investig. 2023;20(3):212-219.

Objective Atomoxetine and fluoxetine are psychopharmacologic agents associated with loss of appetite and weight. Adenosine monophosphate-activated protein kinase (AMPK) is the cellular energy sensor that regulate metabolism and energy, being...

Original Article

March 22, 2023

Reliability and Validity of Chinese Version of the Perceived Competence Scale for Disaster Mental Health Workforce: A Cross-Sectional Study

Qingqing Xiao, Xiaozhen Song, Xuehua Huang, Xiandong Meng

Psychiatry Investig. 2023;20(3):220-227.

Objective This study aimed to translate the English version of the Perceived Competence Scale for Disaster Mental Health Workforce (PCS-DMHW) into Chinese, and to test its reliability and validity in...

Original Article

March 22, 2023

The Core Symptoms of Adolescents Online and Offline Gambling in South Korea Using Network Analysis

Yunhye Oh, Yoo-Sook Joung, Ji Hyun Baek

Psychiatry Investig. 2023;20(3):228-235.

Objective Adolescent gambling is rapidly increasing recently. However, little is known about the core feature of adolescent gambling that should be the treatment target for adolescents. Thus, the objective of...

Original Article

March 22, 2023

Investigation of the Relationship Between Cognitive Functions and Retinal Findings From Spectral Optical Coherence Tomography in Patients With Schizophrenia and Their Healthy Siblings

Rümeysa Tas¸ delen, Batuhan Ayık, Hatice Kaya, Neslihan Sevimli

Psychiatry Investig. 2023;20(3):236-244.

Objective Retinal structural changes which were investigated by optical coherence tomography (OCT) have been reported in schizophrenia. Since cognitive dysfunction is a core feature of schizophrenia, the correlations between retinal...

Original Article

March 22, 2023

Differences in Functional Level and Central Symptom of Network Structures in the Patients Seeking Treatment for Panic Disorder Before and During the COVID-19 Pandemic

Hyun-Ju Kim, Minji Bang, Chun Il Park, Chongwon Pae, Sang-Hyuk Lee

Psychiatry Investig. 2023;20(3):245-254.

Objective Mental health problems such as anxiety, panic, and depression have been exacerbated by the coronavirus disease-2019 (COVID-19). This study aimed to compare the symptom severities and overall function before...

Original Article

March 22, 2023

Childhood Sexual Abuse and Cortical Thinning in Adults With Major Depressive Disorder

Jinyi Kim, Changju Lee, Youbin Kang, Wooyoung Kang, Aram Kim, Woo-Suk Tae, Byung-Joo Ham, Jisoon Chang, Kyu-Man Han

Psychiatry Investig. 2023;20(3):255-261.

Objective A growing body of evidence reports on the effect of different types of childhood abuse on the structural and functional architecture of the brain. In the present study, we...

Original Article

March 22, 2023

Prevalence of Mental Disorders and Associated Factors in Korean Adults: National Mental Health Survey of Korea 2021

Soo Jung Rim, Bong-Jin Hahm, Su Jeong Seong, Jee Eun Park, Sung Man Chang, Byung-Soo Kim, Hyonggin An, Hong Jin Jeon, Jin Pyo Hong, Subin Park

Psychiatry Investig. 2023;20(3):262-272.

Objective Mental health is a global concern and needs to be studied more closely. We aimed to estimate the prevalence of mental disorders and their associated factors among the general...

Original Article

March 22, 2023

Electroconvulsive Seizure Normalizes Motor Deficits and Induces Autophagy Signaling in the MPTP-Induced Parkinson Disease Mouse Model

Seonghoo Huh, Hyun Sook Yu, Nuree Kang, Yong Min Ahn, Yong Sik Kim, Se Hyun Kim

Psychiatry Investig. 2023;20(3):273-283.

Objective Electroconvulsive seizure (ECS) is a potent treatment modality for various neuropsychiatric diseases, including Parkinson disease (PD). Recent animal studies showed that repeated ECS activates autophagy signaling, the impairment of...

Original Article

March 22, 2023

Pilot Study About the Effects of the Soma Experiencing Motion (Soma e-Motion) Program on Interoceptive Awareness and Self-Compassion

Mi-Sun Lee, Sun Je Kim, Jeong-Ho Chae, Soo-Young Bhang, Mimi Lee, Hyeong Beom Kim, Hyu Jung Huh

Psychiatry Investig. 2023;20(3):284-292.

Objective The purpose of this study was to examine the effects of the Soma experiencing motion (Soma e-motion) program on interoceptive awareness and self-compassion among novices. Methods A total of 19...