Epigenetic Regulation of BDNF Gene in Response to Stress
Manabu Fuchikami, Shigeto Yamamoto, Shigeru Morinobu, Shiro Takei, Shigeto Yamawaki
Psychiatry Investig. 2010;7(4):251-256.   Published online 2010 Dec 13     DOI: https://doi.org/10.4306/pi.2010.7.4.251
Understanding hippocampal neural plasticity in captivity: Unique contributions of spatial specialists
Leslie S. Phillmore, Sean D. T. Aitken, Broderick M. B. Parks
Learning & Behavior.2022; 50(1): 55.     CrossRef
Adaptation-induced plasticity in the sensory cortex
Vishal Bharmauria, Afef Ouelhazi, Rudy Lussiez, Stéphane Molotchnikoff
Journal of Neurophysiology.2022; 128(4): 946.     CrossRef
Drinking Pattern in Intermittent Access Two-Bottle-Choice Paradigm in Male Wistar Rats Is Associated with Exon-Specific BDNF Expression in the Hippocampus During Early Abstinence
Danil Peregud, Mikhail Stepanichev, Natalia Gulyaeva
Journal of Molecular Neuroscience.2021; 71(2): 262.     CrossRef
Neuroprotective effect of Val variant of BDNF Val66Met polymorphism on hippocampus is modulated by the severity of menstrual pain
Wei-Chi Li, Hsiang-Tai Chao, Ming-Wei Lin, Horng-Der Shen, Li-Fen Chen, Jen-Chuen Hsieh
NeuroImage: Clinical.2021; 30: 102576.     CrossRef
Slamming the sham: A Bayesian model for adaptive adjustment with noisy control data
Andrew Gelman, Matthijs Vákár
Statistics in Medicine.2021; 40(15): 3403.     CrossRef
Effects of a multimodal exercise protocol on functional outcomes, epigenetic modulation and brain-derived neurotrophic factor levels in institutionalized older adults: a quasi-experimental pilot study
Iasmin Fraga, Camila Weber, WéritonBaldo Galiano, Lucio Iraci, Mariana Wohlgemuth, Gabriela Morales, Camila Cercato, Juliana Rodriguez, Daniela Pochmann, Caroline Dani, Pérsia Menz, AdrianeDal Bosco, VivianeRostirola Elsner
Neural Regeneration Research.2021; 16(12): 2479.     CrossRef
Effects of Morphine and Maternal Care on Behaviors and Protein Expression of Male Offspring
Ardeshir Akbarabadi, Mitra-Sadat Sadat-Shirazi, Mohamed Kabbaj, Setareh Nouri Zadeh-Tehrani, Solmaz Khalifeh, Fardad Pirri, Mohammad-Reza Zarrindast
Neuroscience.2021; 466: 58.     CrossRef
Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice
Oriana Maria Maurel, Sebastiano Alfio Torrisi, Cristina Barbagallo, Michele Purrello, Salvatore Salomone, Filippo Drago, Marco Ragusa, Gian Marco Leggio
International Journal of Molecular Sciences.2021; 22(10): 5157.     CrossRef
Oxidative Dysregulation in Early Life Stress and Posttraumatic Stress Disorder: A Comprehensive Review
Evangelos Karanikas, Nikolaos P. Daskalakis, Agorastos Agorastos
Brain Sciences.2021; 11(6): 723.     CrossRef
Glucocorticoid Signaling and Epigenetic Alterations in Stress-Related Disorders
Niki Mourtzi, Amalia Sertedaki, Evangelia Charmandari
International Journal of Molecular Sciences.2021; 22(11): 5964.     CrossRef
Histone deacetylase inhibition reduces ventral tegmental area dopamine neuronal hyperexcitability involving AKAP150 signaling following maternal deprivation in juvenile male rats
Ryan D. Shepard, Ludovic D. Langlois, Michael E. Authement, Fereshteh S. Nugent
Journal of Neuroscience Research.2020; 98(7): 1457.     CrossRef
A valepotriate-enriched fraction from Valeriana glechomifolia decreases DNA methylation and up-regulate TrkB receptors in the hippocampus of mice
Liz G. Müller, Caroline Biojone, Amanda J. Sales, Andresa H. Betti, Vivian Herzfeldt, Sâmia R.L. Joca, Stela M.K. Rates
Behavioural Pharmacology.2020; 31(4): 333.     CrossRef
TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons
Hang Liu, Lei Peng, Joan So, Ka Hing Tsang, Chi Ho Chong, Priscilla Hoi Shan Mak, Kui Ming Chan, Siu Yuen Chan
Molecular Neurobiology.2019; 56(4): 2640.     CrossRef
Enriched gestation activates the IGF pathway to evoke embryo-adult benefits to prevent Alzheimer’s disease
Enjie Liu, Qiuzhi Zhou, Ao-Ji Xie, Mengzhu Li, Shujuan Zhang, Hezhou Huang, Zhenyu Liuyang, Yali Wang, Bingjin Liu, Xiaoguang Li, Dongsheng Sun, Yuping Wei, Xiaochuan Wang, Qun Wang, Dan Ke, Xifei Yang, Ying Yang, Jian-Zhi Wang
Translational Neurodegeneration.2019;[Epub]     CrossRef
Stress Across Generations: DNA Methylation as a Potential Mechanism Underlying Intergenerational Effects of Stress in Both Post-traumatic Stress Disorder and Pre-clinical Predator Stress Rodent Models
Sriya Bhattacharya, Audrey Fontaine, Phillip E. MacCallum, James Drover, Jacqueline Blundell
Frontiers in Behavioral Neuroscience.2019;[Epub]     CrossRef
Brain Regional and Temporal Changes in BDNF mRNA and microRNA-206 Expression in Mice Exposed to Repeated Cycles of Chronic Intermittent Ethanol and Forced Swim Stress
Matthew G. Solomon, William C. Griffin, Marcelo F. Lopez, Howard C. Becker
Neuroscience.2019; 406: 617.     CrossRef
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
Ciaran P.C. Galts, Luis E.B. Bettio, David C. Jewett, Charles C. Yang, Patricia S. Brocardo, Ana Lucia S. Rodrigues, Jonathan S. Thacker, Joana Gil-Mohapel
Neuroscience & Biobehavioral Reviews.2019; 102: 56.     CrossRef
Dysregulation of BDNF in Prefrontal Cortex in Alzheimer’s Disease
Toby Aarons, Steven Bradburn, Andrew Robinson, Antony Payton, Neil Pendleton, Chris Murgatroyd
Journal of Alzheimer's Disease.2019; 69(4): 1089.     CrossRef
Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones
Karem H. Alzoubi, Zeinab Y. Al Subeh, Omar F. Khabour
Behavioural Brain Research.2019; 369: 111930.     CrossRef
Extracellular Vesicles Derived from Lactobacillus plantarum Increase BDNF Expression in Cultured Hippocampal Neurons and Produce Antidepressant-like Effects in Mice
Juli Choi, Yoon-Keun Kim, Pyung-Lim Han
Experimental Neurobiology.2019; 28(2): 158.     CrossRef
Deficiency in Androgen Receptor Aggravates the Depressive-Like Behaviors in Chronic Mild Stress Model of Depression
Hung, Huang, Chang, Kang
Cells.2019; 8(9): 1021.     CrossRef
Epigenome Interactions with Patterned Neuronal Activity
Jillian Belgrad, R. Douglas Fields
The Neuroscientist.2018; 24(5): 471.     CrossRef
Methyl Donors Supplementation Attenuates the Adverse Effects of Maternal High Fructose Diet of Offspring Emotional and Cognitive Behaviors
Sidi Mohamed Coulibaly, Abdelhalem Mesfioui, Ali Ouichou, Pacôme Kouadio N’Go, Amina El Hasnaoui, Abdeljabbar Nassiri, Aboubaker El Hessni
Open Journal of Endocrine and Metabolic Diseases.2017; 07(11): 203.     CrossRef
Behavioral, emotional and neurobiological determinants of coronary heart disease risk in women
Viola Vaccarino, J. Douglas Bremner
Neuroscience & Biobehavioral Reviews.2017; 74: 297.     CrossRef
Ketamine induces brain-derived neurotrophic factor expression via phosphorylation of histone deacetylase 5 in rats
Miyeon Choi, Seung Hoon Lee, Min Hyeop Park, Yong-Seok Kim, Hyeon Son
Biochemical and Biophysical Research Communications.2017; 489(4): 420.     CrossRef
Predator-based psychosocial stress animal model of PTSD: Preclinical assessment of traumatic stress at cognitive, hormonal, pharmacological, cardiovascular and epigenetic levels of analysis
Phillip R. Zoladz, David M. Diamond
Experimental Neurology.2016; 284: 211.     CrossRef
Genetics of Tinnitus: An Emerging Area for Molecular Diagnosis and Drug Development
Jose A. Lopez-Escamez, Thanos Bibas, Rilana F. F. Cima, Paul Van de Heyning, Marlies Knipper, Birgit Mazurek, Agnieszka J. Szczepek, Christopher R. Cederroth
Frontiers in Neuroscience.2016;[Epub]     CrossRef
Cognitive Impairment in Patients with Psoriasis: A Cross-Sectional Study Using the Montreal Cognitive Assessment
Emine Colgecen, Asuman Celikbilek, Dudu Taslak Keskin
American Journal of Clinical Dermatology.2016; 17(4): 413.     CrossRef
Brain-derived neurotrophic factor and early-life stress: Multifaceted interplay
Natalya P Bondar, Tatiana I Merkulova
Journal of Biosciences.2016; 41(4): 751.     CrossRef
Early life stress increases stress vulnerability through BDNF gene epigenetic changes in the rat hippocampus
Mi Kyoung Seo, Nguyen Ngoc Ly, Chan Hong Lee, Hye Yeon Cho, Cheol Min Choi, Le Hoa Nhu, Jung Goo Lee, Bong Ju Lee, Gyung-Mee Kim, Bong June Yoon, Sung Woo Park, Young Hoon Kim
Neuropharmacology.2016; 105: 388.     CrossRef
Stress Response and Perinatal Reprogramming: Unraveling (Mal)adaptive Strategies
Laura Musazzi, Jordan Marrocco
Neural Plasticity.2016; 2016: 1.     CrossRef
Serum S100B as a Surrogate Biomarker in the Diagnoses of Burnout and Depression in Emergency Medicine Residents
Bedia Gulen, Mustafa Serinken, Cenker Eken, Özgür Karcıoglu, Okkes Taha Kucukdagli, Elif Kilic, Guleser Akpinar, Suleyman Nogay, Mahmut Kuh, James R. Miner
Academic Emergency Medicine.2016; 23(7): 786.     CrossRef
A role for histone acetylation mechanisms in adolescent alcohol exposure-induced deficits in hippocampal brain-derived neurotrophic factor expression and neurogenesis markers in adulthood
Amul J. Sakharkar, Ryan P. Vetreno, Huaibo Zhang, Dadasaheb M. Kokare, Fulton T. Crews, Subhash C. Pandey
Brain Structure and Function.2016; 221(9): 4691.     CrossRef
Spinal Plasticity and Behavior: BDNF-Induced Neuromodulation in Uninjured and Injured Spinal Cord
Sandra M. Garraway, J. Russell Huie
Neural Plasticity.2016; 2016: 1.     CrossRef
Effects of chronic variable stress on cognition and Bace1 expression among wild-type mice
Z A Cordner, K L K Tamashiro
Translational Psychiatry.2016; 6(7): e854.     CrossRef
The potential of epigenetics in stress-enhanced fear learning models of PTSD
Ashley M. Blouin, Stephanie E. Sillivan, Nadine F. Joseph, Courtney A. Miller
Learning & Memory.2016; 23(10): 576.     CrossRef
Molecular mechanisms underlying the memory-enhancing effects of estradiol
Karyn M. Frick
Hormones and Behavior.2015; 74: 4.     CrossRef
Epigenetics and learning
Birgitta Mc Ewen
Trends in Neuroscience and Education.2015; 4(4): 108.     CrossRef
Decreased brain-derived neurotrophic factor plasma levels in psoriasis patients
A.R. Brunoni, P.A. Lotufo, C. Sabbag, A.C. Goulart, I.S. Santos, I.M. Benseñor
Brazilian Journal of Medical and Biological Research.2015; 48(8): 711.     CrossRef
Maternal deprivation disrupts mitochondrial energy homeostasis in the brain of rats subjected to ketamine-induced schizophrenia
Alexandra Ioppi Zugno, Felipe Damázio Pacheco, Josiane Budni, Mariana Bittencourt de Oliveira, Lara Canever, Alexandra Stephanie Heylmann, Patrícia Gomes Wessler, Flávia da Rosa Silveira, Gustavo Antunes Mastella, Cinara Ludwig Gonçalves, Karoline V. Frei
Metabolic Brain Disease.2015; 30(4): 1043.     CrossRef
Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder
Naimesh Solanki, Isam Alkadhi, Fatin Atrooz, Gaurav Patki, Samina Salim
Nutrition Research.2015; 35(1): 65.     CrossRef
Acute stress affects the global DNA methylation profile in rat brain: Modulation by physical exercise
Gelson M. Rodrigues, Leandro V. Toffoli, Marcelo H. Manfredo, José Francis-Oliveira, Andrey S. Silva, Hiviny A. Raquel, Marli C. Martins-Pinge, Estefânia G. Moreira, Karen B. Fernandes, Gislaine G. Pelosi, Marcus V. Gomes
Behavioural Brain Research.2015; 279: 123.     CrossRef
Epigenetic mechanisms underlying the role of brain-derived neurotrophic factor in depression and response to antidepressants
Florian Duclot, Mohamed Kabbaj, Hans H. Hoppeler
Journal of Experimental Biology.2015; 218(1): 21.     CrossRef
Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease
Tomoyuki Nagata, Nobuyuki Kobayashi, Jumpei Ishii, Shunichiro Shinagawa, Ritsuko Nakayama, Nobuto Shibata, Bolati Kuerban, Tohru Ohnuma, Kazuhiro Kondo, Heii Arai, Hisashi Yamada, Kazuhiko Nakayama
Dementia and Geriatric Cognitive Disorders Extra.2015; 5(1): 64.     CrossRef
Activation-induced cytidine deaminase regulates activity-dependent BDNF expression in post-mitotic cortical neurons
Vikram S. Ratnu, Wei Wei, Timothy W. Bredy
European Journal of Neuroscience.2014; 40(7): 3032.     CrossRef
Methyl Donor-Deficient Diet during Development Can Affect Fear and Anxiety in Adulthood in C57BL/6J Mice
Daisuke Ishii, Daisuke Matsuzawa, Shingo Matsuda, Haruna Tomizawa, Chihiro Sutoh, Eiji Shimizu, Cheryl S. Rosenfeld
PLoS ONE.2014; 9(8): e105750.     CrossRef
Altered DNA methylation status of human brain derived neurotrophis factor gene could be useful as biomarker of depression
Yixuan Song, Koichi Miyaki, Tomoko Suzuki, Yasuharu Sasaki, Akizumi Tsutsumi, Norito Kawakami, Akihito Shimazu, Masaya Takahashi, Akiomi Inoue, Chiemi Kan, Sumiko Kurioka, Takuro Shimbo
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.2014; 165(4): 357.     CrossRef
17β-Estradiol regulates histone alterations associated with memory consolidation and increases Bdnf promoter acetylation in middle-aged female mice
Ashley M. Fortress, Jaekyoon Kim, Rachel L. Poole, Thomas J. Gould, Karyn M. Frick
Learning & Memory.2014; 21(9): 457.     CrossRef
Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene
N Perroud, A Salzmann, P Prada, R Nicastro, M-E Hoeppli, S Furrer, S Ardu, I Krejci, F Karege, A Malafosse
Translational Psychiatry.2013; 3(1): e207.     CrossRef
Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum
S J James, Svitlana Shpyleva, Stepan Melnyk, Oleksandra Pavliv, I P Pogribny
Translational Psychiatry.2013; 3(2): e232.     CrossRef
Reversible epigenetic histone modifications and Bdnf expression in neurons with aging and from a mouse model of Alzheimer’s disease
Michael P. Walker, Frank M. LaFerla, Salvador S. Oddo, Gregory J. Brewer
AGE.2013; 35(3): 519.     CrossRef
Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging
Ayesha Maqbool, Michael Lattke, Thomas Wirth, Bernd Baumann
Molecular Neurodegeneration.2013;[Epub]     CrossRef
Alterations in Brain-Derived Neurotrophic Factor in the Mouse Hippocampus Following Acute but Not Repeated Benzodiazepine Treatment
Stephanie C. Licata, Nina M. Shinday, Megan N. Huizenga, Shayna B. Darnell, Gavin R. Sangrey, Uwe Rudolph, James K. Rowlett, Ghazaleh Sadri-Vakili, Ryan K Bachtell
PLoS ONE.2013; 8(12): e84806.     CrossRef
Aberrant Histone Deacetylase2–Mediated Histone Modifications and Synaptic Plasticity in the Amygdala Predisposes to Anxiety and Alcoholism
Sachin Moonat, Amul J. Sakharkar, Huaibo Zhang, Lei Tang, Subhash C. Pandey
Biological Psychiatry.2013; 73(8): 763.     CrossRef
Decreased serum levels of brain-derived neurotrophic factor in adults with attention-deficit hyperactivity disorder
Margarida Corominas-Roso, Josep A. Ramos-Quiroga, Marta Ribases, Cristina Sanchez-Mora, Gloria Palomar, Sergi Valero, Rosa Bosch, Miguel Casas
International Journal of Neuropsychopharmacology.2013; 16(6): 1267.     CrossRef
Region-specific expression of brain-derived neurotrophic factor splice variants in morphine conditioned place preference in mice
Min Meng, Xinhan Zhao, Yonghui Dang, Jingyuan Ma, Lixu Li, Shanzhi Gu
Brain Research.2013; 1519: 53.     CrossRef
Epigenetic regulation of the BDNF gene: implications for psychiatric disorders
F Boulle, D L A van den Hove, S B Jakob, B P Rutten, M Hamon, J van Os, K-P Lesch, L Lanfumey, H W Steinbusch, G Kenis
Molecular Psychiatry.2012; 17(6): 584.     CrossRef
Epigenetic changes brought about by perinatal stressors: A brief review of the literature
Blase Billack, Ryan Serio, Ilton Silva, Craig H. Kinsley
Journal of Pharmacological and Toxicological Methods.2012; 66(3): 221.     CrossRef
Effects of citalopram on serotonin and CRF systems in the midbrain of primates with differences in stress sensitivity
Cynthia L. Bethea, Fernanda B. Lima, Maria L. Centeno, Karin V. Weissheimer, Olga Senashova, Arubala P. Reddy, Judy L. Cameron
Journal of Chemical Neuroanatomy.2011; 41(4): 200.     CrossRef
Antioxidants Prevent Memory Deficits Provoked by Chronic Variable Stress in Rats
Bárbara Tagliari, Emilene B. Scherer, Fernanda R. Machado, Andréa G. K. Ferreira, Carla Dalmaz, Angela T. S. Wyse
Neurochemical Research.2011; 36(12): 2373.     CrossRef